
VSL® Probiotics: A Legacy of Science in Every Strain.
Building on the trusted heritage of VSL#3®, VSL®Probiotics now includes innovative supplements like VSL4®, designed for everyday wellness.
VSL#3® Benefits:
A Clinically Studied Medical FoodVSL#3° is a medical-grade formulation supported byclinical research.
Ultra-High Potency, Guaranteed
Contains 112.5 billion live bacteria (CFU) per capsulean ultra-high-potency formula designed to keep itslabeled potency through expiration when stored underrecommended conditions.
Multi-Strain
8 complementary strains from 3 different genera.
Formulated with Care.Free from Compromise.
More Than a Probiotic.A Powerful Medical Food.
Pioneers in Probiotics. Leaders in Gut Health.
VSL#3®is an ultra-high-potency probiotic medical food — and the #1 gastroenterologist-recommended multi-strain probiotics brand.†Developed for people with serious gastrointestinal conditions, it’s trusted by healthcare professionals and customers alike for its scientific foundation, clinical credibility, and unwavering quality.
Built on Science. Proven in Practice.
Driven by research — not marketing trends — VSL#3®is trusted in clinical care for the dietary management of specific gastrointestinal conditions. It continues to set the standard for potency, consistency, and reliability in probiotic therapy.
Ultra-High-Potency. Guaranteed.
VSL#3®products deliver between 112.5 billion and 900 billion live bacteria per serving, depending on the formulation. Unlike many probiotics that only promise potency at the time of manufacture, VSL#3®guarantees potency through expiration when stored as directed.
Clinically Researched Formulas.Real-World Results.
Each VSL#3®product combines 8 well-characterized probiotic strains from 3 genera to help maintain a balanced intestinal microbiota and support digestive health. The VSL#3®family is specially designed for the dietary management of irritable bowel syndrome (IBS), ulcerative colitis (UC), and pouchitis.
Why Doctors Trust VSL#3®
VSL#3® Is Scientifically Formulated For The Dietary Management of IBS
Doctor Recommended
In a 2002 survey of gastroenterologists, 93% reported that IBS patients were satisfied with VSL#3.
The most frequently observed benefits:
Less bloating
Reduced pain
Better stool consistency and frequency
Overall symptom improvement
Clinically Studied and FODMAP Friendly Certified for the Dietary Management of IBS
In a 2021 clinical study, VSL#3®showed outcomes comparable to those achieved with a low FODMAP diet² — a commonly recommended but restrictive approach. Because VSL#3®is certified FODMAP Friendly, it can also be used alongside a low FODMAP diet for flexible dietary management.
1. Data on file 2. Ankerson L, et al. J Med Internet Res. 2021; 23(12): e30291.
SHOP NOWIt’s What’s on the Inside
Our unique8-strain formulationis designed so each strain complements the others, helping maintain a balanced gut microbiota. Billions of live, beneficial bacteria work together to support digestive health.
VSL#3® Capsules:Clean Ingredients. Verified Quality.
Free From Common Irritants:
- Dairy-Free
- Gluten-Free
- Soy-Free
- Nut-Free
- No GMOs
- Vegan
Certified for Peace of Mind:
- FODMAP Friendly Certified
- Halal Certified
- Kosher Certified
Science Over Hype.Purpose Over Promises.
Built on the legacy of VSL#3®— a probiotic trusted by healthcare professionals and recognized for its scientific rigor — VSL® Probiotics continues to advance microbiome science through targeted, high-quality formulations that support both clinical dietary management and everyday wellness.
Collapsible content
Committed to Potency
Committed to Potency
Potent probiotic formulations guaranteed tomaintain labeled CFU counts throughexpiration.
For us, potency isn't a number -it's a principle.Every VSL® Probiotics formulation is developedwith meaningful levels of live bacteria,manufactured under controlled conditions, andverified to maintain the labeled CFU count throughexpiration when stored as recommended. Potencymatters because probiotic function depends onboth the quantity and vitality of live organisms thatreach the gut. Even modest loss over time canaffect performance, which is why every VSL®Probiotics product is designed and tested to deliverconsistent strength from first dose to last.
Designed for Viability
Designed for Viability
Garefully designed fofmulations that helpsafeguard live bacteria from production todelivery.
For probiotics to work, live microorganisms mustsurvive both storage and digestion to reach the gutintact. Every VSL® Probiotics formulation isdeveloped with this in mind- combining carefullyselected strains, stability-enhancing formulationdesign, and packaging to maintain viability frommanufacturing through expiration.VSL#3® is maintained under strict cold-chainconditions -refrigerated throughout production,storage, and shipping -to help preserve livestrains at their intended strength.VSL4® products are shelf-stable and formulatedwith acid-resistant capsules that help protectprobiotic bacteria until they reach the intestinaltract.
Science-Led Strain Selection
Science-Led Strain Selection
Thoughtfully formulated with complementaryprobiotic strains chosen for function andpurpose.
Our formulations are grounded in science. Eachstrain is selected for its documented characteristicsand ability to contribute meaningfully to a balancedmicrobiome. This approach draws on years ofprobiotic research -building on well-studiedformulations and evidence-backed strains to createproducts designed for specific microbiome needs.Across the VSL® Probiotics family, everyformulation follows the same principle: scienceguides each step, from strain selection to finishedproduct. This consistent, evidence-based processensures reliability and quality across the brand'sentire portfolio.
A Legacy of Expertise
A Legacy of Expertise
A probiotic heritage recognized for itsconsistency, credibility, and professionaltrust.
VSL® Probiotics builds on the legacy of VSL#3®a formulation long trusted by healthcareprofessionals for its quality and reliability. Thatfoundation continues to guide how we developevery product in the VSL® Probiotics family.Our focus is clear: to create formulations groundedin evidence, crafted with precision, and respectedfor their consistency-not driven by trends, but bytrust earned through experience.
Committed to Potency
Committed to Potency
Potent probiotic formulations guaranteed tomaintain labeled CFU counts throughexpiration.
For us, potency isn't a number -it's a principle.Every VSL® Probiotics formulation is developedwith meaningful levels of live bacteria,manufactured under controlled conditions, andverified to maintain the labeled CFU count throughexpiration when stored as recommended. Potencymatters because probiotic function depends onboth the quantity and vitality of live organisms thatreach the gut. Even modest loss over time canaffect performance, which is why every VSL®Probiotics product is designed and tested to deliverconsistent strength from first dose to last.
Designed for Viability
Designed for Viability
Carefully designed formulations that helpsafeguard live bacteria from production todelivery.
For probiotics to work, live microorganisms mustsurvive both storage and digestion to reach the gutintact. Every VSL® Probiotics formulation isdeveloped with this in mind-combining carefullyselected strains, stability-enhancing formulationdesign, and packaging to maintain viability frommanufacturing through expiration.VSL#3® is maintained under strict cold-chainconditions -refrigerated throughout production,storage, and shipping -to help preserve livestrains at their intended strength.VSL4® products are shelf-stable and formulatedwith acid-resistant capsules that help protectprobiotic bacteria until they reach the intestinaltract.